The date is set, the venue is booked. Now, what to wear down the aisle?

Shopping for a bridal gown can be exciting for any bride-to-be, but with so many choices out there -- silhouettes, necklines, fabrics, colors -- it's easy to see how it could also become overwhelming.

So, how (and where?) to find that perfect one? Jennie Ma, fashion editor at TheKnot.com, gave us a few tips to help guarantee you'll say "yes" to the right dress.

When to start shopping:

Brides should start looking for gowns eight months before they say "I do," Ma advised. That allows for time to find the right dress, as well as the fittings and alterations you'll need to ensure it looks perfect on the big day.

"It takes time to find the right dress. Some girls are lucky and they find it right away, but it does take longer for a lot of other brides. Definitely give yourself time -- you don't want to feel rushed," she added.

Where to look:

There are a number of different places where brides can look for a bridal gown, all offering different kinds of dresses and experiences.

High-end salons will carry all the top designers and give brides an intimate shopping experience, but it's not the place for a bride-to-be on a budget, Ma said.

Brides can also look for their dress at department stories, which can be a one-stop shop for the entire bridal party -- bridesmaids' dresses can also be found there, and the groom can find everything he needs as well. Some department stores also have partnerships with high-end designers (like Roses by Reem Acra at Nordstrom), offering dresses at more affordable prices.

Brides can also go the retail route, looking at lines offered by companies like J. Crew and Ann Taylor. "They're really great because they have amazing price points and it's another place where you can fully service your entire bridal party and get all the outfits in one place," said Ma.

How to figure out what you want:

Brides can find inspiration on websites like TheKnot.com, with galleries showing all the latest gowns from top designers. Magazines and 동두천출장마사지 - https://www.anmaop.com/%de%a0-%eb%8f%99%eb%91%90%ec%b2%9c%ec%b6%9c%ec%9e... Pinterest are other places where brides can look through pictures and see what they like -- and, perhaps more importantly, what they don't like.

But other factors from your wedding will also play into the decision-making process.

"I would say the first thing is to figure out your venue and what style you're going for, and that naturally will really help you narrow down what dress you're looking for," Ma said. "If you're getting married in this gorgeous ballroom, you know you need a really dramatic gown. You're not going to want something really simple. So that will inform the decision."

When you go -- be open-minded:

Personal style preferences, budget and the type of wedding a bride is having will all influence what kind of dress she wants. But, brides should still go into the shopping process with an open mind, Ma said.

"It's good to go in knowing what you want. It's good to be prepared and have an idea -- it will help your search process. But at the same time, be open minded," she advised.

So if a friend, family member or bridal consultant suggests you try on a dress, go for it! The worst thing that could happen is you reaffirm that ball gowns aren't your thing. But maybe, just maybe, that mermaid-style gown - http://www.martindale.com/Results.aspx?ft=2&frm=freesearch&lfd=Y&afs=mer... you didn't think would work will wow you.

Four years after getting the vaccine, 94 percent of women were protected from infection with the virus that causes most cervical cancers and none had developed worrisome precancerous conditions, a study showed.

"We're thrilled about these results. The immune responses seem to be really long-lasting," said Dr. Eliav Barr, who leads development of the vaccine for Merck and Co. The company plans to seek U.S. Food and Drug Administration approval next year for an expanded version of the vaccine that also could be used to prevent genital warts in both women and men.

The new study was funded by Merck and led by University of Washington researchers who presented results Monday at a meeting of the American Society for Microbiology.

"They showed clear effectiveness," said Dr. Scott Hammer, a Columbia University infectious disease expert who reviewed the work but has no ties to Merck or the study. "This is a very important issue for women's health around the world."

If the vaccine makes it to market, 안양출장안마 - https://www.softanma.com/11-anyang it would be the second developed to prevent cancer. The hepatitis B vaccine has dramatically reduced the number of infections that progress to liver cancer.

Cervical cancer strikes nearly half a million women worldwide each year and kills about half. In the United States, about 15,000 women get it and about 5,000 die.

Virtually all cases are caused by infection with human papilloma virus, or HPV, which is spread through sex. One strain, HPV-16, accounts for about half of all cervical cancers.

A previous study showed that HPV-16 infections were completely prevented in 768 women who had received the Merck vaccine 18 months earlier. None developed precancerous conditions either.

The new study followed 755 of these women for four years after vaccination. HPV-16 infections had taken hold in seven; none developed precancers. In a comparison group of 750 women who received dummy shots, infections took hold in 111 and precancers formed in 12.

Even though protection had waned for a small number of women in the study, the vaccine's effectiveness was still very high, said Dr. Douglas Lowy, a National Cancer Institute scientist who invented the vaccine. The government gave rights to develop it to two companies — Merck and GlaxoSmithKline — and Merck's work is a little farther along, Lowy said

r>

r>
"Revaccination might be advisable at some point," but it will take more study to know whether that is necessary or would improve effectiveness, he said

r>

r>
Women in the study were ages 16 to 23 when they received the vaccine, given in three doses over six months

r>

r>
"Most people think it would be recommended for young adolescents. The idea would be you would immunize people relatively soon before they become sexually active," because the germ is spread through sex, Lowy said

r>

r>
Meanwhile, Merck is in the final stages of testing an expanded vaccine. Besides HPV-16, it contains strain 18, which causes another 10 percent to 20 percent of cervical cancers, as well as strains that cause genital warts in men and women, and penile and anal cancers in men

r>

r>
About 25,000 women and men have been enrolled in that study in 34 countries, and results are expected next year, Barr said

r>

r>
Giving the vaccine to men would not only prevent disease in them but also would prevent infections in their partners, said Steven Projan, a drug development expert with Wyeth who helped review research for the microbiology meeting. The vaccine also might prevent women already infected - https://www.academia.edu/people/search?utf8=%E2%9C%93&q=infected with HPV from developing cancer, he said.

The date is set, the venue is booked. Now, what to wear down the aisle?

Shopping for a bridal gown can be exciting for any bride-to-be, but with so many choices out there -- silhouettes, necklines, fabrics, colors -- it's easy to see how it could also become overwhelming - http://www.wired.com/search?query=overwhelming .

So, how (and where?) to find that perfect one? Jennie Ma, fashion editor - https://openclipart.org/search/?query=fashion%20editor at TheKnot.com, gave us a few tips to help guarantee you'll say "yes" to the right dress.

When to start shopping:

Brides should start looking for gowns eight months before they say "I do," Ma advised. That allows for time to find the right dress, as well as the fittings and 광양출장마사지 - https://www.toptopanma.com/%ea%b4%91%ec%96%91%ec%98%a4%ed%94%bc%ea%b1%b8... alterations you'll need to ensure it looks perfect on the big day.

"It takes time to find the right dress. Some girls are lucky and they find it right away, but it does take longer for a lot of other brides. Definitely give yourself time -- you don't want to feel rushed," she added.

Where to look:

There are a number of different places where brides can look for a bridal gown, all offering different kinds of dresses and experiences.

High-end salons will carry all the top designers and give brides an intimate shopping experience, but it's not the place for a bride-to-be on a budget, Ma said.

Brides can also look for their dress at department stories, which can be a one-stop shop for the entire bridal party -- bridesmaids' dresses can also be found there, and the groom can find everything he needs as well. Some department stores also have partnerships with high-end designers (like Roses by Reem Acra at Nordstrom), offering dresses at more affordable prices.

Brides can also go the retail route, looking at lines offered by companies like J. Crew and Ann Taylor. "They're really great because they have amazing price points and it's another place where you can fully service your entire bridal party and get all the outfits in one place," said Ma.

How to figure out what you want:

Brides can find inspiration on websites like TheKnot.com, with galleries showing all the latest gowns from top designers. Magazines and Pinterest are other places where brides can look through pictures and see what they like -- and, perhaps more importantly, what they don't like.

But other factors from your wedding will also play into the decision-making process.

"I would say the first thing is to figure out your venue and what style you're going for, and that naturally will really help you narrow down what dress you're looking for," Ma said. "If you're getting married in this gorgeous ballroom, you know you need a really dramatic gown. You're not going to want something really simple. So that will inform the decision."

When you go -- be open-minded:

Personal style preferences, budget and the type of wedding a bride is having will all influence what kind of dress she wants. But, brides should still go into the shopping process with an open mind, Ma said.

"It's good to go in knowing what you want. It's good to be prepared and have an idea -- it will help your search process. But at the same time, be open minded," she advised.

So if a friend, family member or bridal consultant suggests you try on a dress, go for it! The worst thing that could happen is you reaffirm that ball gowns aren't your thing. But maybe, just maybe, that mermaid-style gown you didn't think would work will wow you.

The FDA also instructed employees to block imports of the supplements, 아산출장마사지 - https://www.anmapop.com/%ec%95%84%ec%82%b0%ec%b6%9c%ec%9e%a5%ec%83%b5%cf... calling them "dangerous ... and even life-threatening." The agency said the supplement bears the name Yilishen when it is imported from China and is sold as Actra-Rx within the United States.

Laura Alvey, an FDA spokeswoman, declined further comment saying the matter is under investigation that may lead to criminal or civil enforcement actions.

Actra-Rx and Yilishen are promoted on Web sites as erectile dysfunction treatments that enhance men's sexual performance, the FDA said.

Despite an all-natural label, Actra-Rx capsules contain prescription strength levels of sildenafil, the active drug ingredient in Viagra, according to a letter published in the Journal of the American Medical Association.

Viagra, produced by Pfizer, was approved by the FDA to treat erectile dysfunction. The recommended dose is 50 milligrams. Some men take as little as 25 mg. or as much as 100 mg.

According to "Sex, Lies and Niagra," published in the Feb. 4, 2004 issue of JAMA, chemical analyses found an average of 55 milligrams of sildenafil per capsule of Actra-Rx and Niagra Actra-Rx, another name under which the product has been sold.

"The use of such nonprescription substances may present health risks for individuals with contraindications to the use of sildenafil," wrote the authors.

Follow up testing by the FDA confirmed Actra-Rx contained prescription-strength levels of sildenafil.

A spokesman for Los Angeles-based Body Basics declined comment. The company's voicemail identifies them as manufacturer of Actra-Rx. The company's Web site continues to advertise Actra-Rx as a "natural sexual enhancer" available in starter kits of 10 pills for $78.99.

In June 2003, Pfizer filed - http://www.shewrites.com/main/search/search?q=Pfizer%20filed a trademark infringement suit against Body Basics, which had been using the name Niagra to sell the supplement. The federal court, in a consent judgment, barred the company from using that name, said Bryant Haskins, director of corporate media relations at Pfizer.

When the FDA in March 27, 1998 approved Viagra, the first pill to treat impotence, it warned consumers not to use the drug in combination with products containing nitrates to avoid worrisome lowering of blood pressure.

According to the FDA, the sildenafil in Actra-Rx also can interact with certain prescription drugs that contain nitrates or nitrates in illicit substances, significantly lowering blood pressure to unsafe levels.

Men at risk include those with diabetes, high blood pressure, high cholesterol or heart disease. Those individuals use medications that contain nitrates and often suffer erectile dysfunction.

The FDA advised people who have taken Actra-Rx or Yilishen to stop using it and to consult a doctor regarding an alternate erectile dysfunction treatment.

Thinking of having a destination wedding? Planning one involves a lot of the same things as a traditional wedding -- choosing a guest list, selecting a venue, finding a florist, photographer and so on -- but doing so from another country adds another layer of difficulty into the mix.

Sarah Pease, owner and creative director of Brilliant Event Planning in New York City (which specializes in destination weddings in Ireland and Spanish-speaking locales) spoke to CBSNews.com and detailed some of the most important to-dos when it comes to saying "I do" abroad.

The first thing couples should do when planning a destination wedding is figure out the guest list, according to Pease.

"Before you can start hunting for locations, you need to know how many people you're accommodating," she explained.

Keeping in mind where guests will be traveling from is also important when choosing a wedding - http://www.traveldescribe.com/?s=wedding location, Pease added. For example, if the bride's family is based in a big city, they'll have more destinations and flight times easily available to them than a groom's family based in a small town elsewhere.

Which brings us to location, location, location. Couples should be sure to research the legality of getting married - http://www.tumblr.com/tagged/married in their destination of choice -- and consider making a stop at their local courthouse before hopping an international flight.

"By and large, most of my couples are getting their civil ceremony done in the U.S. beforehand, because so many -- like Mexico, for example -- have crazy requirements when it comes to having a legal marriage," said Pease.

Another thing to consider when choosing a wedding locale: your religious affiliation. If a couple is getting married in a country where Catholicism is the main religion, for example, they may have a hard time finding a rabbi.

Once a destination is determined, when should couples begin planning? "That depends on your guest list and how important it is for certain guests to be there," Pease said. "Rule of thumb is six months or more, but plenty of couples if they're just doing more of an elopement destination -- where it's maybe just the bride and groom and immediate family -- that can be done in as little as six weeks before."

If couples decide to hire a planner, that person can help with everything from organizing flight information and ground transportation to traditional wedding tasks like finding the right florist and making sure everything is delivered correctly and promptly.

It might not be easy to find those perfect vendors (florist, photographer, makeup artist, etc) when planning from afar, but Pease noted, "If you have a wedding planner who has strong contacts and has done their homework, they should be able to find you people." In bigger countries there will be a wide variety of people ready and eager to help, but those may be harder to come by on smaller islands -- and 목포출장마사지 - https://www.toptopanma.com/%eb%aa%a9%ed%8f%ac%ec%98%a4%ed%94%bc%ea%b1%b8... while it could sometimes be easier to bring your own vendors along for the trip, some countries, like Bermuda, require you to use local ones.

Planning a wedding in another country also means being aware of that country's customs and culture, and anticipating that things may move slower in around-the-world locales than they do in the U.S. Getting a response to a request that might seem simple -- like whether or not the salad can be done without tomato, or making sure the officiant has a microphone for the ceremony -- could take longer than couples may expect.

And when it comes to planning out the details of the big day, Pease added, couples should be "overly specific" to ensure nothing gets lost in translation.

"Vendors in foreign countries might not 'know' what you mean when you're talking about your bouquet, or dance floor layout or how you want the chairs arranged. When possible, send photos or sketches or whatever it may be," she advised. "What we may consider standard might not be the case in other places. So these are all things that you'll have to keep in mind as you're planning -- be very specific about what your expectations are, because otherwise you may be disappointed."

Nonpowder guns kill an average of four Americans yearly, 군포출장마사지 - https://www.anmapop.com/%ea%b5%b0%ed%8f%ac%ec%b6%9c%ec%9e%a5%ec%83%b5%cf... and from 1990 to 2000, there were 39 such deaths — 32 of children younger than 15, according to a report in November's issue of Pediatrics.

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The report, published Monday, comes just two weeks after the BB gun death of an 8-year-old South Carolina boy accidentally killed by a 13-year-old friend. The pellet pierced the boy's heart, said Richland County Coroner Gary Watts.

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"These are not the kinds of BB guns that I grew up with," Watts said. Today's BB guns "are extremely high-powered," and some can shoot with a velocity nearly matching a .22 caliber rifle, Watts said.

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Nonpowder guns include powerful air rifles introduced in the 1970s and paintball pistols used in war games. They're sometimes described as fake guns and often given to children as gifts, but the report says they can cause internal injuries.

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Nationally, an estimated 21,840 injuries related to nonpowder guns were treated in emergency departments in 2000 — most in children aged 5 to 14, according to the report prepared by the American Academy of Pediatrics' Committee on Injury, Violence and Prevention

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Data from the Centers for Disease Control and Prevention show there were 19,163 nonpowder gun injuries last year

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Most states have laws or regulations governing nonpowder guns. New York's is one of the strictest, prohibiting the purchase or unsupervised use by someone younger than 16 years, the Pediatrics report said

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While some models of air guns - http://www.buzzfeed.com/search?q=air%20guns and BB guns are marketed specifically to youngsters, manufacturers and sellers also stress that they should be handled like legitimate firearms

r>

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The gun involved in the South Carolina shooting was a present from the older boy's parents, who had hoped it would lift his spirits after his own brother's - http://www.covnews.com/archives/search/?searchthis=brother%27s recent death in a car accident, Watts said

r>

r>
"They're being given as toys without recognition that there may be a serious injury risk," said report author Dr. Danielle Laraque, a New York pediatrician.

Four years after getting the vaccine, 94 percent of women were protected from infection with the virus that causes most cervical cancers and none had developed worrisome precancerous - http://www.stockhouse.com/search?searchtext=worrisome%20precancerous conditions, a study showed.

"We're thrilled about these results. The immune responses seem to be really long-lasting," said Dr. Eliav Barr, who leads development of the vaccine for Merck and Co. The company plans to seek U.S. Food and Drug Administration approval next year for an expanded version of the vaccine that also could be used to prevent genital warts in both women and men.

The new study was funded by Merck and led by University of Washington researchers who presented results Monday at a meeting of the American Society for Microbiology.

"They showed clear effectiveness," said Dr. Scott Hammer, a Columbia University infectious disease expert who reviewed the work but has no ties to Merck or the study. "This is a very important issue for women's health around the world."

If the vaccine makes it to market, it would be the second developed to prevent cancer. The hepatitis B vaccine has dramatically reduced the number of infections that progress to liver cancer.

Cervical cancer strikes nearly half a million women worldwide each year and kills about half. In the United States, about 15,000 women get it and about 5,000 die.

Virtually all cases are caused by infection with human papilloma virus, or HPV, which is spread through sex. One strain, HPV-16, accounts for about half of all cervical cancers.

A previous study showed that HPV-16 infections were completely prevented in 768 women who had received the Merck vaccine 18 months earlier. None developed precancerous conditions either.

The new study followed 755 of these women for four years after vaccination. HPV-16 infections had taken hold in seven; none developed precancers. In a comparison group of 750 women who received dummy shots, infections took hold in 111 and precancers formed in 12.

Even though protection had waned for a small number of women in the study, the vaccine's effectiveness was still very high, said Dr. Douglas Lowy, a National Cancer Institute scientist who invented the vaccine. The government gave rights to develop it to two companies — Merck and GlaxoSmithKline — and Merck's work is a little farther along, 문경출장마사지 - https://www.anmaweb.com/%eb%ac%b8%ea%b2%bd%ec%98%a4%ed%94%bc%ea%b1%b8%e2... Lowy said

r>

r>
"Revaccination might be advisable at some point," but it will take more study to know whether that is necessary or would improve effectiveness, he said

r>

r>
Women in the study were ages 16 to 23 when they received the vaccine, given in three doses over six months

r>

r>
"Most people think it would be recommended for young adolescents. The idea would be you would immunize people relatively soon before they become sexually active," because the germ is spread through sex, Lowy said

r>

r>
Meanwhile, Merck is in the final stages of testing an expanded vaccine. Besides HPV-16, it contains strain 18, which causes another 10 percent to 20 percent of cervical cancers, as well as strains that cause genital warts in men and women, and penile and anal cancers in men

r>

r>
About 25,000 women and men have been enrolled in that study in 34 countries, and results are expected next year, Barr said

r>

r>
Giving the vaccine to men would not only prevent disease in them but also would prevent infections in their partners, said Steven Projan, a drug development expert with Wyeth who helped review research for the microbiology meeting. The vaccine also might prevent women already infected with HPV from developing cancer, he said.

"There arrives a point in time when the procedure should simply be done. We submit that that time is now," the researchers wrote in an article scheduled for publication Friday in The American Journal of Bioethics. The procedure attaches the face of a dead donor to someone with a severely disfigured face, such as a burn or accident victim.

The doctors said they don't have a prime candidate for 창원출장마사지 - https://www.anmaweb.com/%ec%b0%bd%ec%9b%90%ec%98%a4%ed%94%bc%ea%b1%b8%e2... the procedure, and they are not actively screening for candidates.

They have submitted an application to an institutional review board in the Netherlands and are nearly ready to submit one to an independent board in the United States.

The Louisville doctors said they would not perform the transplant without approval from one of the boards, which are designed to protect medical research subjects' - http://www.broowaha.com/search/subjects%27 rights.

"The people we're considering are people who have no other options," Dr. John H. Barker, director of plastic surgery research at the University of Louisville, told The Courier-Journal newspaper.

Nichola Rumsey of the University of the West of England, an expert in psychosocial issues in medicine, said the ethical issues of the procedure have yet to be fully explored - http://www.ajaxtime.com/?s=explored . She wrote one of 14 essays written in reaction to the article and published in the bioethics journal.

"Previous research and current understanding indicate that the psychological risks are more complex and extensive than the Louisville team suggest," she wrote. "I have no wish to minimize the distress experienced by many people with severe disfigurements, but to my mind, the current risk/benefit ratio ... is dubious at best."

Besides Louisville, such transplants are being considered by teams in Cleveland, England and France.

The date is set, the venue is booked. Now, what to wear down the aisle?

Shopping for a bridal gown can be exciting for any bride-to-be, but with so many choices out there -- silhouettes, necklines, fabrics, colors -- it's easy to see how it could also become overwhelming.

So, how (and where?) to find that perfect one? Jennie Ma, fashion editor at TheKnot.com, gave us a few tips to help guarantee you'll say "yes" to the right dress.

When to start shopping:

Brides should start looking for gowns eight months before they say "I do," Ma advised. That allows for time to find the right dress, as well as the fittings and alterations you'll need to ensure it looks perfect on the big day.

"It takes time to find the right dress. Some girls are lucky and they find it right away, but it does take longer for a lot of other brides. Definitely give yourself time -- you don't want to feel rushed," she added.

Where to look:

There are a number of different places where brides can look for a bridal gown, all offering different kinds of dresses and experiences.

High-end salons will carry all the top designers and give brides an intimate shopping experience, but it's not the place for a bride-to-be on a budget, Ma said.

Brides can also look for their dress at department stories, which can be a one-stop shop for the entire bridal party -- bridesmaids' dresses can also be found there, and the groom can find everything he needs as well. Some department stores also have partnerships with high-end designers (like Roses by Reem Acra at Nordstrom), 대구출장안마 - https://www.opanma.com/10-daegu offering dresses at more affordable prices.

>\

>
Brides can also go the retail route, looking at lines offered by companies like J. Crew and Ann Taylor. "They're really great because they have amazing price points and it's another place where you can fully service your entire bridal party and get all the outfits in one place," said Ma.

>\

>
How to figure out what you want:

>\

>
Brides can find inspiration on websites like TheKnot.com, with galleries showing all the latest gowns from top designers. Magazines and Pinterest are other places where brides can look through pictures and see what they like -- and, perhaps more importantly, what they don't like.

>\

>
But other factors - http://www.answers.com/topic/factors from your wedding will also play into the decision-making process.

>\

>
"I would say the first thing is to figure out your venue and what style you're going for, and that naturally will really help you narrow down what dress you're looking for," Ma said. "If you're getting married in this gorgeous ballroom, you know you need a really dramatic gown. You're not going to want something really simple. So that will inform the decision."

>\

>
When you go -- be open-minded:

>\

>
Personal style preferences, budget and the type of wedding a bride is having will all influence what kind of dress she wants. But, brides should still go into the shopping process with an open mind, Ma said.

>\

>
"It's good to go in knowing what you want. It's good to be prepared and have an idea -- it will help your search process. But at the same time, be open minded," she advised.

>\

>\

>\

>
So if a friend, family member or bridal consultant suggests you try on a dress, go for it! The worst thing that could happen is you reaffirm that ball gowns aren't your thing. But maybe, just maybe, that mermaid-style gown you didn't think would work will wow you.