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Many doctors fail to screen women

The study involved 149,524 white postmenopausal women, age 65 on average, who had bone density scans. Of the 2,259 who broke bones during the following year, 82 percent had initial bone-density scores indicating thinning bones but not osteoporosis.

Only 18 percent of women with fractures had scores at or above the threshold many doctors use to define osteoporosis and to prescribe drugs.

The study was led by Dr. Ethel Siris at Columbia-Presbyterian Medical Center and included researchers from Merck & Co., which makes the osteoporosis drug Fosamax and funded the study. A Merck doctor participated in a committee that oversaw the study design and analysis, Siris said.

Experts not involved in the study said the data appear sound.

The researchers suggested doctors consider lowering the threshold for prescribing osteoporosis drugs, 카지노사이트 - https://urbanbasis.com/ especially for women who have certain risk factors that increase their chances of breaking - https://www.change.org/search?q=breaking a bone.

"My goal is not to sell medicine; my goal is to inform the debate," Siris said.

The research appears in Monday's Archives of Internal Medicine.

Dr. Leonard Serebro of Ochsner Clinic Foundation cautioned that while drug treatment can help prevent fractures in women with full-blown disease, more evidence is needed to show the same benefit in women with milder bone loss.

Women's risk of developing osteoporosis increases as they enter menopause and lose the bone-protecting effects of estrogen.

The National Osteoporosis Foundation recommends bone density screening for all women 65 and older and for younger postmenopausal women with at least one other osteoporosis risk factor, including smoking, low weight and family history of hip fracture.

Many doctors fail to screen women. And when doctors do the tests, they often do not prescribe medicine unless the results indicate full-blown osteoporosis — a bone-density score of minus 2.5 or less, the researchers said.

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They said a more reasonable approach would be using National Osteoporosis Foundation guidelines recommending that medication be considered for women with scores of minus 2 or less; or minus 1.5 or less for those with at least one risk factor.

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However, bone-building medication - https://twitter.com/search?q=bone-building%20medication&src=typd costs around $70 monthly and some insurers will not cover it if women do not have full-blown osteoporosis, Serebro said.

Men were slightly older - 67 compared to 62 for women - when the cancer was found, and the disease was typically in its later stages when discovered in men

In the past 25 years, 카지노사이트 - http://0318.company/ the number of cases in the United States climbed 26 percent, according to the largest study so far on the disease - http://sportsrants.com/?s=disease to date - on more than 2,500 American men with the disease. It was published Monday in the online version of Cancer, the American Cancer Society's journal.

"We didn't know before this that male breast cancer was increasing," said study author Dr. Sharon Giordano, oncologist and assistant professor of medicine at the University of Texas' M.D. Anderson Cancer Center in Houston. "It remains a very rare disease, even though it's gone up."

U.S. male breast cancer rates rose from 8.6 cases per 1 million men in the 1970s to 10.8 cases per 1 million in the 1990s. The study covered 1973-98. The increase was much smaller than that for women, who saw a 52 percent increase in breast cancer cases.

The study raises suspicion that obesity may be responsible for the breast cancer increase in both sexes, said Dr. Michael Thun, epidemiology chief at the Atlanta-based cancer society.

That's because breast cancer has risen for men without the traditional reasons for the rise of female breast cancer, such as increased mammography and use of postmenopausal hormones such as estrogen, which has been linked to breast cancer.

But the waistlines of all Americans are growing. "Fat tissue produces estrogen," which in turn can lead to breast cancer, said Thun, who was not involved in the latest study.

The study also found that men tended to be diagnosed with breast cancer later than women, likely because screening is not common. Men were slightly older - 67 compared to 62 for women - when the cancer was found, and the disease was typically in its later stages when discovered in men.

Despite this, cancer experts say the breast cancer risk for men remains low enough that they should be more concerned with common killers, such as heart disease and lung, prostate and colorectal cancers - http://search.usa.gov/search?affiliate=usagov&query=colorectal%20cancers .

"When you have an increase in a rare cancer, you still have a rare cancer," said Thun. "Given the rarity of disease, it's far more important to have screening for colorectal cancer and to avoid smoking" than to focus on breast cancer in men.

Self-exams aren't necessary for men. But if a man finds a lump in his breast, has nipple discharge or bleeding, he needs to see a doctor, Giordano said.

By Daniel Yee

But it's had a bad side effect." Governments in some developing nations are taking steps

In an astonishing testament to globalization, this outbreak of girth is occurring just as doctors are winning the fight against a number of vexing diseases.

Except in the poorest nations of Africa, new drugs and improved public health have corralled, if not cured, infectious diseases like smallpox, malaria and influenza that used to kill millions.

Now a new enemy is emerging in the 21st century: our appetite. Around the globe, about 1.7 billion people should lose weight, according to the International Obesity Task Force. Of those who are overweight, about 312 million are obese - at least 30 pounds over their top recommended weight.

Already, a third of all deaths globally are from ailments linked to weight, lack of exercise and smoking. And perhaps most worrisome is obesity's spread beyond wealthy western nations.

From the glaciers of Iceland to the palm-fringed beaches of the Philippines, there are now more fat people in the world than hungry people. And in extreme cases, people who are heavy since childhood could die as much as five to 10 years early.

"What's clear is that the developing world in particular is going to bear the enormous brunt of this weight gain," said Neville Rigby, policy director of the obesity task force.

"It's rapidly accelerating. We're even seeing obesity in adolescents in India now. It's universal. It has become a fully global epidemic - indeed, a pandemic."

U.S. nutrition scientist Barry Popkin agrees. He serves as a key adviser to the World Health Organization, which will propose the first global strategy on diet, physical activity and health next week at its annual meeting in Geneva, Switzerland.

"When you find nary a country that's being missed, nary a rural area that's being missed, let alone an urban area," Popkin said, "you've got to say it's more than an epidemic."

No Country Immune

Certainly the United States remains a nation of scale-busters, with two of every three Americans overweight.

But there are a dozen places even worse:

Soon China will be the world's biggest country in more ways than sheer population, experts predict. It's a stunning reversal from the Mao Zedong era when as many as 40 million people starved in the Great Leap Forward famine of 1958-61.

Pursuing a new doctrine of a "well-off society," Chinese cities represent the world's biggest growth market for restaurants that until recently were considered to be counterrevolutionary. Now a new KFC, Pizza Hut or Taco Bell opens almost every day. Virtually every mainland home now has a television blaring junk food ads.

When university student Li Guangxu was a baby, rice was rationed. Now he eats cookies for breakfast.

Shopping at a CarreFour supermarket in western Shanghai, the solidly built young man fills a shopping cart with cookies, potato chips, soda and beer. The bustling new store devotes 12 aisles to snacks, including the bulk bins and freezers stocked with crackers, candy, and ice cream.

"I like these things. They taste great," Li said. "I don't have time for anything else. Older folks don't eat this stuff, but we do. We like snacks."

Most scientists believe our bodies have retained a prehistoric tendency to store fuel for periods of deprivation. Modern foods are so plentiful and 카지노사이트 - http://0318.company/ so packed with calories that getting fat might be biologically difficult to avoid.

But the problem is rooted in something deeper than nutrition math. Pleasure and emotional comfort are basic instincts, and eating tends to stimulate those circuits in the brain, not unlike addictive drugs.

A food fix always is within arm's reach.

Hardware emporiums host parking lot barbecues, and airports sell gooey, hot cinnamon rolls. Gas stations have morphed into grocery stores, and grocery stores have ballooned into warehouses. You can buy potato chips whether you are trekking - http://pixabay.com/en/new-zealand-waterfall-nature-trekking/ in Nepal or paddling a chocolate-brown river in Borneo's tropical jungles.

Who can resist? Almost no one.

"I compare the propensity to eat as somewhere between the propensity to breathe and the propensity to have sex," said Stephen Bloom, chief of metabolic medicine at the University of London's Imperial College. "Just saying, 'Stop eating!' doesn't work. It's much worse than stopping smoking."

Weight's Health Effects

Simply being fat won't necessarily kill you outright. And it's not weight alone that determines your risk from several diseases. But being overweight carries severe consequences.

Diabetes, heart disease and some cancers have been linked to weight, and all are on the rise.

Type 2 Diabetes is the illness most directly linked to obesity. A condition that often leads to heart disease and kidney failure, it is blamed for more than 3 million deaths a year. It afflicts 154 million people - nearly four times the number who have HIV or AIDS - and the WHO forecasts more than twice as many people will develop diabetes in the next 25 years.

Obesity can triple the risk of heart disease. One-third of all deaths globally - about 17 million - are blamed on heart disease, stroke and related cardiovascular problems, WHO figures show.

Some scientists predict it will outstrip infectious killers by the end of the decade.

Countries with extensive health care have stalled the onset of heart disease into old age and saved lives. But in much of the world, the latest drugs and arterial scouring procedures are not widely available.

In those countries, fatal heart attacks and strokes are much more common among younger, working age adults.

Researchers from Columbia University's Earth Institute examined Brazil, China, India, South Africa and the Russian republic of Tartarstan. They found that the heart disease death rate for adults ages 30-59 was up to twice as high as the U.S. rate. Among Russians in the study, the rate was up to five times higher.

Obesity was cited as a primary factor, along with smoking, lack of exercise and untreated high blood pressure. The researchers described the influence of unhealthy diets as "surprising."

"Never before ... have so many people been at risk of premature death," they wrote.

In South Africa, 11 percent of the population has HIV. Yet cardiovascular disease there still accounts for a higher rate of death among men and women under age 45.

Over the next 30 years, the trend in those counties is projected to worsen.

In India, more than a quarter of the 5 million people who die from heart attacks and strokes every year are younger than 65. This exceeds U.S. rates in the 1950s before aggressive cardiac care and prevention, said study co-author Susan Raymond.

Obesity also plays a significant, if poorly understood, role in many cancers. WHO data shows cancer accounts for about 12.5 percent of the world's deaths, and that rate is expected to increase dramatically, mostly in developing countries.

The fact that obesity is on the rise in these countries as well is due to a confluence of factors that researchers say must be examined.

The global trend toward weight gain and its associated illnesses is not restricted to the well-off. High-fat, high-starch foods tend to be cheaper, so poor people eat more of them.

In Mexico, 40 percent of its 105 million people live in poverty. Yet two-thirds of men and women there are overweight or obese.

In the slums of Sao Paulo, Brazil, 30 percent of the schoolchildren in 500 poor families have stunted growth due to poor diet. Yet, reports the Pan American Health Organization, about 6 percent of the children and 9 percent of the adults were obese, too.In southern Africa, Zambia, which experienced a food crisis in 2002, reports that 10 percent to 15 percent of urban schoolchildren are obese.

"It's a myth that you can't have poverty and obesity coexisting," said Tufts University nutritionist Bea Rogers.

How It Happened

Many factors contribute to the widening of the world's waistline.

"For the last 150 years we've been getting fatter," said Bloom. But now, he says, "everything has kind of come together."

For starters, there is cheap, plentiful food. In developing countries, people still spend 40 percent of their income on food, as opposed to 15 percent by American families.

But even in poor nations, the relative cost of eating is declining as the world's farmers are able to grow huge quantities of grain that is quickly processed and shipped without spoilage.

According to U.N. figures, the consumption of oils and fats over the last 30 years has doubled and is forecast to keep growing.

"In the developing world, it happened overnight," said WHO adviser Popkin, who heads nutrition epidemiology at the University of North Carolina. "One year they had very expensive butter and the next year edible oil came on the scene. It was a tenth of a cost and all of a sudden for very little money you could make your food taste better."

Nutritionists say more and cheaper sugar is another factor, despite the industry's strenuous denials.

James E. Tillotson, director of Tufts University's Food Policy Institute, calculates - http://ms-jd.org/search/results/search&keywords=calculates/ the average American drinks the equivalent of a 55-gallon drum of soda every year, compared to 20 gallons of sweetened beverages a year in 1970.

Increases almost as dramatic have occurred in Europe, and soft drink factories are increasingly popping up in developing countries.

Tillotson, who developed fruit-based drinks for Ocean Spray in the 1980s, says the beverage industry did not consider the health ramifications of their now-ubiquitous products.

"We never thought people would abuse them," he said. "What everybody wanted and liked has become dangerous."

Slowly, the food industry is responding.

McDonald's has healthier menus and is phasing out super-sizing. Kraft Foods, whose products range from Oreos to Jell-O in 150 countries, has a scientific advisory panel. Among the company's initiatives: capping the portion size of single-serving packaging.

Much of Big Food's response comes after failed efforts by obese people to sue fast-food chains for damages.

"A lot of chief executives are really in a state of shock right now," said international nutrition expert Andrew Prentice of the London School of Hygiene and Tropical Medicine. "They've produced this stuff, cheaper and cheaper, feeding the world. All of a sudden, we're saying, 'Stop doing this!"'

Another factor is how food is promoted and distributed. Brightly packaged brands that remain safe for months have widely replaced fresh bulk foods sold in community markets.

In 1990, no more than 15 percent of food bought in Latin America came from supermarkets. Now, 60 percent is from six supermarket chains.

Experts say that because the changes occurred so rapidly and medical care is so lagging, the developing world's obesity problem - combined with more cigarette smoking - could be both public health and economic disasters in countries that were verging on prosperity.

There are demographic changes, too. In many nations, women joining the work force created a demand for convenience foods.

"We already are tired from working and we buy only packaged foods," said Bertha Rodriguez of Mexico City. The 61-year old great-grandmother is a widow who supports herself by frying quesadillas in a streetside stand. One health concession: She now uses vegetable oil instead of lard.

"Before, we were at home preparing something light and nutritious," she said.

Technology Triumphs

People spend more time sitting in the car, at the computer and especially in front of the television - an average of 1,669 hours a year in the United States, a habit that is extending internationally.

With such low activity levels, as little as 100 extra calories a day translates into 10 pounds in a year.

"Physical activity is not on the front burner in many people's minds, said Stephen Blair, research director at the Cooper Institute of Aerobics Research in Dallas.

Technology is changing people's activity levels even in the poorest nations, where backbreaking work and hauling water from the community well was the norm.

In China's megacities, crowds once pedaled identical black bicycles to work. Now adults drive cars and ride trains and buses. In southeast Asia, farmers are replacing water buffalo plows with tiny tractors, and choosing crop chemicals over hand cultivation.

"It was done with the best of intentions," Bloom said. "Telephones, cars, computers all come from the freedom from hunger and fear. But it's had a bad side effect."

Governments in some developing nations are taking steps.

Singapore schools have added physical activities and replaced soft drinks with bottled water. Brazil is making school lunch programs serve fruits and vegetables.

Such efforts are among those the World Health Organization says will be necessary to prevent a worldwide crisis.

But it's a battle against human nature.

Experts say it's unreasonable to expect people with 21st century lifestyles and desires to return to a leaner, 1950s-era silhouette.

"It would be a huge public health achievement if we simply stopped the weight gain where it is now," Blair said.

"I think that's what we're stuck with."

By Emma Ross, Joseph Verrengia, Elaine Kurtenbach and Morgan Lee

He said he was surprised that the generic drugs, which usually are transported in armored cars, were being stored so carelessly

Dan Smoot, chief detective for an anti-drug task force in eastern Kentucky, said undercover narcotics investigators began purchasing the generic drug from street-level dealers earlier this week. Investigators suspect a shipment - http://www.covnews.com/archives/search/?searchthis=shipment of the drug was stolen from a storage building in eastern Kentucky.

"When we first got the pills, we didn't know what they were," Smoot said. "They look nothing like the OxyContin we were familiar with."

OxyContin is a long-lasting version of oxycodone, a narcotic considered important therapy for many patients suffering chronic, moderate to severe pain from illnesses such as cancer. The tablet, when swallowed whole, provides 12 hours of pain relief.

But the drug can produce a quick and potentially lethal high if it is chewed, snorted or injected. It has been linked to more than 100 deaths and bears the government's strongest warning label.

The Food and Drug Administration has given approval for Teva Pharmaceuticals of North Wales, Pa., and Endo Pharmaceuticals of Chadds Ford, Pa., to sell generic versions of the drug.

Law enforcement officials were dreading the release of the generic version, saying it could increase availability and reduce prices of the drug on the black market.

Karen Engle, executive director 카지노사이트 - https://www.sunleethailand.com/ of Operation UNITE, said the anti-drug task force is investigating the origin of the generic drug now available illegally in Kentucky.

"We actually had to call the poison control center to have them identify the substance for us," she said.

The generic drugs circulating in the mountain region may have been a stolen shipment intended for pharmacies in the region, Smoot said.

Kentucky State Police Detective Eddie Crum said a generic drug shipment was taken during an April 29 break-in at a storage facility in Pikeville. He said he was surprised that the generic drugs, which usually are transported in armored cars, were being stored so carelessly.

"We knew when the FDA approved generic OxyContin that it would end up in the region," Engle said. "But we didn't think it would be here before the pharmacies got it."

By Roger Alford

The marijuana is free

"It's my happy dance!" she says, throwing her arms around her husband Mike.

She has also planted an acre of marijuana.

The decision that lets the crop remain is just one round in a long legal battle.

Last month, a federal judge in San Jose issued a preliminary injunction banning the Justice Department, including the Drug Enforcement Administration, from interfering with the Corrals' pot garden, set above an ocean bluff near Davenport, 카지노사이트 - http://pgneetindia.com/ about an hour south of San Francisco. The injunction gives the judge time to reconsider his earlier decision to allow the garden to be uprooted.

Still, the Corrals call the injunction a victory.

They share their harvest through the first legally recognized, nonprofit medical marijuana club in America, which they founded in 1993. The club has about 250 seriously ill members who have prescriptions from their doctors to use marijuana to alleviate their suffering, increase their appetites and control their seizures. The marijuana is free.

The San Jose ruling is one of a number challenging federal restrictions on medical marijuana, which has consistently won support in national opinion polls since 1995 but has had a mixed record in state ballot measures.

This summer, the U.S. Supreme Court is expected to decide whether to hear another case that could undo or affirm the Corrals' right to grow pot — granted by state and local regulations, but denied by federal law. A second case in federal court in San Francisco — in which other medicinal-use growers seek to reclaim seized marijuana — could also affect the coupl

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The Justice Department refused commen

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For now, the Corrals are the only people in the United States growing marijuana in their backyard backed by state law, a local ordinance and a federal judge's injunction. And Valerie Corral has become a heroine to proponents of medical marijuan

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"This could be the moment of the beginning of the end of this insane war against the sick," said Bruce Mirken of the Washington D.C.-based advocacy group Marijuana Policy Project. "And while the DEA and the Justice Department characterize Valerie as a common drug dealer, all you have to do is spend two minutes with her to know that's a lie

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During the past three decades, while sharing marijuana with sick people, Corral has watched — and in many cases held — 140 friends, ranging in age from 7 to 96, as they died of cancer, AIDS and other illnes

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"It is the greatest honor to be asked by a person who is dying to sit with them," she s

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Reflection on those deaths has given her strength, she said — while battling the government, when federal agents pointed a rifle at her head, and when her motives have been called into ques

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"John Ashcroft is not someone I would have chosen to tangle with, but I think of him, and George Bush, as lost souls," she said. "When I look at them, I think about how they are just people, ... and that makes them less fearsome. Ultimately we all make the same journey, and ultimately I hope they make theirs in pe

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In fact, Corral's compassion is grudgingly respected at the DEA's San Francisco of

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"I'm personally impressed with her desire to help deathly ill people," said spokesman Richard Meyer. "It's just that she makes it look like the way to help sick and dying people is to give them marijuana. And that's not the

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"There's hundreds of ways to help these people. The DEA has a lot of compassion for those people who are sick and dying, but I think there are many, many ways to help them without giving them mariju

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At DEA headquarters, authorities said the issue has nothing to do with Valerie Corral or compas

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"This may be personal to her, but it's not personal to the DEA," said the agency's Will Glaspy in Washington, D.C. "The DEA's job - http://www.travelwitheaseblog.com/?s=DEA%27s%20job is to enforce the Controlled Substance Act. Congress passed the laws and charged us with enforcing them. She is attempting to use the court system to get what she wa

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Valerie Corral's path to becoming a medical marijuana advocate began 31 years ago, the day a small airplane swooped low and buzzed a Volkswagen she was riding in through the Nevada desert. The car went out of control and was sent skidding, rolling and bouncing 365 feet through the dust, brush and r

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Corral's slight body was flung against the roof and doors, causing brain damage, epilepsy, and a lifetime of staggering migraines. She took prescription drugs but still suffered convulsions, shaking and grand mal seiz

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Then one day, Mike handed her a medical journal article that showed marijuana controlled seizures in mice. Since then, for 30 years, Valerie Corral says she has maintained a steady level of marijuana in her sy

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Her legal challenges began in 1992, when the local sheriff arrested her for growing five marijuana plants. With Mike, she challenged the law, using the defense of neces

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Prosecutors dismissed the case, saying they didn't think they could win before a sympathetic jury in liberal Santa Cruz. When the sheriff arrested the Corrals again in 1993, the district attorney said he had no intention of ever prosecuting them and told police to leave them a

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A few years later, the Corrals helped draft California's landmark Compassionate Use Act, approved by voters in 1996, that allows patients with a doctor's recommendation to use marijuana. Similar laws in Alaska, Arizona, Colorado, Hawaii, Maine, Nevada, Oregon and Washington allow the infirm to receive, possess, grow or smoke marijuana for medical purposes without fear of state prosecu

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But the law did not provide complete protection from ar

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While local authorities worked with the Corrals to protect them against theft and coordinate distribution, federal agents continued to assert that growing, using and distributing marijuana was illegal. To provide legal protection, the city of Santa Cruz deputized the Corrals in 2000 to function as medical marijuana provi

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But in September 2002, federal agents raided the Corrals' farm — just weeks before their annual harvest — taking the couple to jail and pulling up more than 150

The Corrals were never charged, but the raid prompted them to begin a legal challenge to the federal ban, aided by a team of attorneys including Santa Clara University law professor Gerald Uelmen and advocates at the Drug Policy Alliance, a non-profit Washington D.C.-based organi

This is the case in which the San Jose judge recently ruled in their

"Representing Valerie Corral, for me, is like representing - http://search.usa.gov/search?affiliate=usagov&query=representing Mother Teresa," said Uelmen, a constitutional law expert, calling her "one of the most compassionate people I've eve

And one who has led a movement to a new

By Martha Mendoza

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