Men in the drug-radiation group had more severe impotence and more breast tissue enlargement than the radiation only group

Almost five years after treatment, six men in the radiation-only study group died of prostate cancer; none of the men who got combined treatment died of prostate cancer. The study involved about 200 men.

Of the more than 200,000 U.S. men diagnosed each year with the disease, nearly half have the kind cancer involved in the study: An exam and imaging indicates it hasn't spread but other tests indicate it might have.

Treatment for such men often involves radiation alone or radiation combined with long-term use of hormone-fighting drugs, often for as long as three years or more. But long-term drug use may cause thinning bones, heart abnormalities that can lead to sudden death and impaired mental function.

The study found that using hormone-blocking drugs for 구례출장안마 - https://www.anmatoto.com/17-pursuit six months had the same survival benefits as long-term use but without the potential health risks. Some men did have side effects including impotence, but that can occur with other prostate cancer - http://wordpress.org/search/prostate%20cancer treatments, including surgery and radiation.

"It's a very important and useful study and should have nearly immediate impact on the fashion in which men are treated," said Dr. Durado Brooks, director of prostate cancer programs at the American Cancer Society.

"Significant numbers of men are getting radiation only," Brooks said. That's partly because many men reject hormone-suppressing drugs when they learn about all the bad side effects from long-term treatment, he said.

Brooks said radiation plus short-term medication is likely to become prevalent given the study results.

Researchers studied 206 men aged 49 to 82 randomly assigned to receive about seven weeks of daily radiation treatments, or radiation plus six months of medication overlapping the radiation treatment. Six of those only on radiation died from prostate cancer while none of those getting combined treatment died from prostate cancer.

More than twice as many radiation-only men had evidence of cancer recurrence, 46 versus 21 in the combined treatment group.

The study by researchers at Boston's Brigham and Women's Hospital and Dana Farber Cancer Institute appears in Wednesday's Journal of the American Medical Association.

The patients had prostate cancer that physical exams and imaging tests indicated had not spread. But they also had high blood levels of PSA - prostate specific antigen - and high Gleason scores, which measure the degree of abnormality found in cancer tissue.

The high levels raise the possibility of cancer elsewhere, said lead author Dr. Anthony D'Amico, a radiation oncologist at both institutions.

The drug treatment studied involved flutamide pills three times daily with periodic injections of either leuprolide acetate or goserelin. The drugs suppress production of testosterone, which can fuel prostate cancer growth.

Men in the drug-radiation group had more severe impotence and more breast tissue enlargement than the radiation only group. But they had no obvious evidence - https://www.behance.net/search?content=projects&sort=appreciations&time=... of the potentially more debilitating complications of long-term treatment. Although those weren't specifically measured, they usually don't appear until after at least a year of treatment, D'Amico said.

In a JAMA editorial, Dr. Theodore DeWeese of Johns Hopkins University, said the study did not address how the drug treatment affected patients' quality of life. He also said the radiation dose was lower than is frequently given, which might explain the differing survival rates.

Still, he called the study "extremely important" because of the survival advantage shown.

By Lindsey Tanner

"Like with any stem cells, the amount of information needed to get us from a stem to a fully developed organ is a lot," said Stanford University biologist Anthony Oro

The project marks the first time that "blank slate" stem cells were able to induce hair growth, said Dr. George Cotsarelis, a University of Pennsylvania dermatologist and co-author 카지노사이트 - http://testemkt.buonny.com.br/mundolog/ of the study.

The study was released Sunday on the Web site of the journal Nature Technology in advance of its April publication date.

"We've shown for the first time these cells have the ability to generate hair when taken from one animal and put into another," Cotsarelis said in a telephone interview. "You can envision a process of isolating existing stem cells and re-implanting them in the areas where guys are bald."

The study confirms what scientists suspected for years: Hair follicles contain "blank slate" stem cells that give most humans a full head of hair for life.

Although they are called stem cells, they differ from embryonic stem cells, the research on which has sparked a political debate because embryos are destroyed in the process. Embryonic stem cells are created in the first days after conception - http://www.purevolume.com/search?keyword=conception and give rise to the human body and its more than 200 different types of cells.

Biologists who study hair because of its regenerative qualities said the new study is an important breakthrough. But they cautioned that a baldness cure is still some years away.

"Like with any stem cells, the amount of information needed to get us from a stem to a fully developed organ is a lot," said Stanford University biologist Anthony Oro. "It will require a lot of things to go right and we are still along way off."

Two drugs now on the market, known commercially as Rogaine and Propecia, were first designed to treat hypertension and enlarged prostates but later were discovered to have hair growth as a side effect. Each drug has about $100 million in sales annually.

It's estimated that more than $1 billion is spent each year in the United States combating baldness, mostly through hair transplants.

The Pacific Tsunami Warning Center said tsunami waves of between 3 and 10 feet were possible along some coasts of New Caledonia and Vanuatu before later lifting the warning

WELLINGTON, New Zealand -- A powerful earthquake that struck in the southern Pacific Ocean on Wednesday sent jitters around the region after authorities warned of possible tsunamis, but there were no initial reports of destructive waves or major damage.

The magnitude 7.5 quake hit in the afternoon near New Caledonia - http://imgur.com/hot?q=Caledonia at a shallow depth, where earthquakes are generally more damaging. It was felt as far away as Vanuatu.

The Pacific Tsunami Warning Center said tsunami waves of between 3 and 파주출장마사지 - https://www.popanma.com/%ed%8c%8c%ec%a3%bc%ec%b6%9c%ec%9e%a5%ec%83%b5%cf... 10 feet were possible along some coasts of New Caledonia and Vanuatu before later lifting the warning.

Judith Rostain, a freelance journalist based in New Caledonia's capital Noumea, said there was no damage to the city and that the threat of a tsunami appeared to have passed. She said the situation remained unclear on the east coast and scattered outer islands.

In Vanuatu, Dan McGarry said he heard only of three small wave surges hitting the southern island of Aneityum. McGarry, the media director at the Vanuatu Daily Post, said the waves traveled only 7 feet beyond the normal tidal waves, and that everybody was fine on the island.

McGarry said he felt the quake where he is based in Vanuatu's capital, Port Vila, as a mild shaking.

"We get a lot of earthquakes every year," he said. "The tsunami warning was what was different this time, though."

The warning center said there was no tsunami threat to Hawaii. It said waves of up to 3 feet were possible in Fiji.

According to the U.S. Geological Survey, the quake struck about 104 miles east of Tadine in New Caledonia at a shallow depth of  6 miles. At least five aftershocks also hit, ranging in magnitude from 5.6 to 6.6. The 6.6 was also six miles down.

The populations of Vanuatu and New Caledonia are similar, with just over 280,000 people living in each archipelago.

Last month, voters in New Caledonia elected to remain a territory of France rather than becoming independent.

Both New Caledonia and Vanuatu sit on the Pacific "Ring of Fire," the arc of seismic faults around the Pacific Ocean where most of the world's earthquakes and volcanic activity occur.

A wicked homage to the scandals of Enron and Tyco and a loopy foreshadowing of the 2008 Wall Street meltdown, "Arrested" premiered in 2003 as a send-up of high-end vanities, greed and corruption as displayed within the Bluth family circle

NEW YORK Portia de Rossi only believed it was happening when her agent got the good news from the producers. Michael Cera only believed it was happening when the cameras rolled.

It happened all right. After years of clamoring from fans and rumors firing them up while the cast hung on for a green light, "Arrested Development" has risen from the dead with 15 half-hours premiering en masse on Netflix on Sunday at 3:01 a.m. ET.

"Arrested Development" is the cock-eyed comedy blessed with a king's ransom of talent and the twisted vision of its mastermind, Mitch Hurwitz, that aired on Fox for three seasons as a cult favorite, then was canceled for low ratings -- and maybe because it befuddled everyone who wasn't hooked on its lunacy. (Those original three seasons are available for streaming on Netflix, too.)

"I think the show scored some 'cool points' for dying before its time," says Cera. "But there are still a lot more places for it to go."

Yes, "Arrested Development" died young with a beautiful, if funny-to-look-at, corpse. But its fans weren't ready to bury it. And said so.

"Clearly a lot of people DIDN'T like the show," Jason Bateman allows, "so I guess all we were hearing from were those who do -- and that happens to be a brand of people who are not afraid of speaking their minds."

Now reanimated by public outcry, "Arrested" is going new places.

"Mitch and the cast didn't want to do something not as good as the old series," says Bateman (who plays Michael Bluth, the fractious family's would-be mediating presence). "We didn't want to do something lateral or just a retread."

"I think it's new at every opportunity," says Cera (who plays Michael Bluth's straight-arrow son), "while retaining the show's original heart."

The new Netflix season takes the form of what you might call an anthology as it updates viewers, character by character with each episode, on the Bluth family -- that once-wealthy, now-broke and at-each-other's-throats clan squabbling in Newport Beach, 의정부출장안마 - https://www.softanma.com/10-council Calif.

A wicked homage to the scandals of Enron and Tyco and a loopy foreshadowing of the 2008 Wall Street meltdown, "Arrested" premiered in 2003 as a send-up of high-end vanities, greed and corruption as displayed within the Bluth family circle.

Besides de Rossi, Cera and Bateman, the cast of "Arrested" Redux brings back Will Arnett, Alia Shawkat, Tony Hale, David Cross, Jeffrey Tambor and Jessica - http://www.thetimes.co.uk/tto/public/sitesearch.do?querystring=Jessica Walter, who reconvened in a strategic yet catch-as-catch-can fashion.

"There was no reality where we could get everybody for a full 7- or 8-month period," explains Hurwitz. "That gave birth to the form we came up with for the new series."

The 15 episodes dwell on individual characters during the six-year span from when the series was canceled in 2006 up through 2012. That structure was supposed to make it simple to book each actor for an isolated shooting schedule.

Then Hurwitz took his creativity another step. Since all the episodes are happening simultaneously, he couldn't resist including crossover appearances from other actors in each episode. He wanted characters and story lines from different episodes to intersect. But his ambition made it all the trickier getting all the actors he needed in place for any given episode.

"In a quarter of the scenes, someone is green-screened in," says Hurwitz, who goes on to concede that what began as a solution to a problem of logistics inspired him to create new problems for himself. For instance: "If two characters are having a conversation in one of those characters' episodes and that character's life changes, then in the other character's episode you show the other side of the conversation and the result of it on THAT character."

The overall effect is a sort of hypertext array for the 15 episodes.

"Mitch made it a choose-your-own-adventure season, in that you can watch any episode out of order and it makes sense but, depending on which order you watch them, the series kind of tells a different story," says de Rossi (who plays spoiled materialist sister Lindsay).

Not that "Arrested Development" has ever chosen the simple or obvious path. From the start, it was dense, convoluted and layered, packed with sight gags, self-referential jokes, flashbacks, hand-held cinematography with run-on sequences (promoting improvisation to enhance Hurwitz's scripts) and, of course, its droll, documentary-like narration by Ron Howard, one of the show's executive producers.

On Fox, the show won six Emmys and a Peabody as well as critics' love while always fighting for its life in the ratings. But Hurwitz is philosophical about the obstacles his show has faced. They seem to have given him license to obliterate boundaries that otherwise would have hemmed him in.

"All of the limitations," he says brightly, "are great creative opportunities."

That applied to the new episodes' shooting pace, which Arnett describes as "run-and-gun and crazy."

"But it really worked to our advantage. It was 'OK, get over here, here we go,' and we were right back into it," says Arnett (who plays Lindsay and Michael's older brother, Gob, a preening, mediocre stage magician). "After working together on the series before, all of us just kind of knew what we're doing. There's an implicit trust there. I know that sounds corny, but it's true."

This is a mutual admiration society: The cast heaps praise on Hurwitz, who volleys it back at his actors. And they all join in celebrating "Arrested" viewers, but for whom the show would be long dead and forgotten.

"There are way, way more fans of 'The Big Bang Theory,'" notes David Cross (who plays Tobias - http://www.google.com/search?q=plays%20Tobias&btnI=lucky Funke, a quack-psychiatrist-turned-actor-wannabe). "But they're not as passionate as 'Arrested Development' fans -- because there's more to be passionate about."

"In either a conscious or unconscious way, our audience thinks -- and rightly so -- it's THEIR show," says Jeffrey Tambor (who plays jailbird-patriarch George Bluth Sr.).

"A lot of people have told me over the years that they would build friendships around the show," Howard adds. "They would judge first dates on whether that person likes 'Arrested Development' or not. It was a means of evaluation."

Does that mean there might be children walking around today whose parents were united by "Arrested Development"?

"I think that's fair to assume," Howard says with a laugh.

"Alex will have a big say in that," Liz Scott said

Alex started selling lemonade four years ago with one stand and raised $2,000 in a single day. Each year brought more stands, manned by friends and volunteers.

The take so far: more than $200,000, including $15,000 brought in last year by the stand at the Scotts' suburban Philadelphia.

"She's determined about anything that's important to her, whether it's what kind of ice cream she's eating or raising money," said Alex's mother, Liz Scott. "I think (the stand) does keep her going sometimes."

This year, on Saturday, all 50 states will have "Alex's Lemonade Stands" open for business. Alex's father, Jay Scott, estimates that as many as 1,000 stands will be pouring - http://bordersalertandready.com/?s=pouring&search=Search the icy cold concoction.

"I think it just shows, you read a lot of bad stuff in the news, it shows how good people really are," Jay Scott said.

Two days before her first birthday, Alex was diagnosed with neuroblastoma, a type of cancer that originates in certain nerve cells. The survival rate for high-risk neuroblastoma, which Alex has, is just 40 percent.

"Alex would have died many years ago if it wasn't for newer experimental therapies, and I think that's something she and her parents recognize," said Dr. John Maris, who has directed Alex's care at the Children's Hospital of Philadelphia. Neuroblastoma is diagnosed in about 700 U.S. children every year.

Though excited about Saturday, Alex has been drained by the chemotherapy and radiation being used to treat a new attack of tumors, her mother said. After seven years of treatment, her cancer is considered incurable.

"She's tired. She's exhausted," Liz Scott said. "Her future has always been uncertain, but I don't think any of us — me, my husband, her doctor — has felt this pessimistic before.

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Because of her frail condition, 카지노사이트 - http://www.motherbabe.com/ her parents and doctor have encouraged Alex to cut back on her fund-raising activities. But she insisted on appearing on a television morning show last Friday to publicize the fifth annual "Alex's Lemonade Stand" day

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After last year's stand, the Scotts put out a call over the Internet for help in every state. Advertising fliers were posted on Alex's Web site, and the Scotts sent out dozens of coupons for free lemonade mix

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Alex has given $150,000 to her Philadelphia hospital. Thousands more have gone for research in Connecticut, Michigan, Texas and California - http://www.sharkbayte.com/keyword/California . This year's take will also go for research, but the family hasn't decided yet where

r>

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"Alex will have a big say in that," Liz Scott said. "She always does.

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Some days Alex feels good, like earlier this week when she saw the new Harry Potter movie. Other days she doesn't. Every day she lives knowing many of her friends have died of neuroblastoma

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Her mom calls Alex "the bravest person I know," and she holds out hope her daughter can overcome her disease

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"I'm obviously very proud of her, but it's more than that," Liz Scott said. "I feel privileged to be her mom. I admire her."

Filipino peacekeepers make "greatest escape" from al Qaeda militants in Syria

MANILA, Philippines - Under cover of darkness, 40 Filipino peacekeepers made a daring escape after being surrounded and under fire for seven hours by Syrian rebels in the Golan Heights, Philippine officials said Sunday, leaving 44 Fijian troops still in the hands of the al Qaeda-linked insurgents - http://search.un.org/search?ie=utf8&site=un_org&output=xml_no_dtd&client... .

"We may call it the greatest escape," Philippine military chief Gen. Gregorio Pio Catapang said.

The peacekeepers became trapped after Syrian rebels entered the U.N.-patrolled buffer zone between Syria and Israel this past week, seizing 44 Fijian soldiers and 카지노사이트 - http://www.fsssmxh.com/ demanding that their Filipino colleagues surrender. The Filipinos, occupying two U.N. encampments, refused and fought the rebels Saturday. The first group of 35 peacekeepers was then successfully escorted out of a U.N. encampment in Breiqa by Irish and Filipino forces on board armored vehicles.

The remaining 40 peacekeepers were besieged at the second encampment, called Rwihana, by more than 100 gunmen who rammed the camp's gates with their trucks and fired mortar rounds. The Filipinos returned fire in self-defense, Philippine military officials said.

More in Syria crisis

At one point, Syrian government forces fired artillery rounds from a distance to prevent the Filipino peacekeepers from being overwhelmed, said Col. Roberto Ancan, a Philippine military official who helped monitor the tense standoff from the Philippine capital, Manila, and mobilize support for the besieged troops.

"Although they were surrounded and outnumbered, they held their ground for seven hours," Catapang said in a news conference in Manila, adding that there were no Filipino casualties. "We commend our soldiers for exhibiting resolve even while under heavy fire."

As night fell and a cease-fire took hold, the 40 Filipinos fled with their weapons, traveling across the chilly hills for nearly two hours before meeting up with other U.N. forces, who escorted them to safety early Sunday, Philippine officials said.

During the siege, the Philippine secretaries of defense and foreign affairs, along with the country's top military brass, gathered at military headquarters in Manila to communicate with the Filipino forces and help guide them out of danger. The Syrian and Israeli governments, along with the United States and Qatar, provided support, the Philippine military said without elaborating.

"If they held their ground, they could have been massacred because they were already running low on ammunition," Defense Secretary Voltaire Gazmin told The Associated Press. "So we discussed with them the option of escape and evasion."

Philippine military officials believed there may have been rebel casualties in the fighting in Rwihana. President Benigno Aquino III, Gazmin said, praised efforts that brought the Filipino peacekeepers to safety but wanted to be sure they could not be targeted by rebel retaliatory attacks.

In New York, the United Nations Disengagement Observer Force, or UNDOF, whose mission is to monitor a 1974 disengagement in the Golan Heights between Israel and Syria, reported that shortly after midnight local time, during a cease-fire agreed with the armed elements, all 40 Filipino peacekeepers left their position and "arrived in a safe location one hour later."

The Filipinos escaped during the cease-fire because they refused to agree to surrender as the insurgents demanded, Philippine military spokesman Lt. Col. Ramon Zagala said.

Another group of 32 Filipino troops that had been trapped at a nearby encampment were extracted on Saturday morning with the help of Irish peacekeepers, the U.N. said.

The clashes erupted after Syrian rebel groups - including al Qaeda's Syrian affiliate, the Nusra Front - overran the Quneitra crossing on the frontier between Syrian- and Israeli-controlled parts of the Golan on Wednesday. A day later, Nusra Front fighters seized 44 Fijian peacekeepers.

In a statement posted on militant websites Sunday, the Nusra Front confirmed that it had seized the Fijians, and posted a photo showing what it said were the captured Fijians in their military uniforms along with 45 identification cards. The group said the men "are in a safe place and in good health, and everything they need in terms of food and medicine is given to them."

The statement mentioned no demands or conditions for the peacekeepers' release.

U.N. Secretary-General Ban Ki-moon on Sunday ensured that the United Nations was doing its utmost to obtain the unconditional and immediate release of the Fijian peacekeepers detained in Golan Heights.

The Nusra Front accused the U.N. of doing nothing to help the Syrian people since the uprising against President Bashar Assad began in March 2011. It said the Fijians were seized in retaliation for the U.N.'s ignoring "the daily shedding of the Muslims' blood in Syria" and even colluding with Assad's army "to facilitate its movement to strike the vulnerable Muslims" through a buffer zone in the Golan Heights.

The U.N. mission has 1,223 troops from six countries: Fiji, India, Ireland, Nepal, Netherlands and the Philippines. A number of countries have withdrawn their peacekeepers due to the escalating violence.

Philippine officials said Filipino forces would remain in Golan until their mission ends in October and not withdraw prematurely following the rebel attacks and the capture of the Fijian peacekeepers.

Both U.N. Secretary-General Ban Ki-moon and the Security Council strongly condemned Saturday's attack on the peacekeepers' positions and the ongoing detention of the Fijian peacekeepers.

The Nusra Front has recently seized hostages to exchange for prisoners detained in Syria and Lebanon.

Late Saturday, the group released four Lebanese soldiers and policemen taken captive earlier this month in a cross-border raid on the frontier town of Arsal, Lebanon's military said.

The Nusra Front and other militants still hold some two dozen Lebanese soldiers and police that they kidnapped in the town of Arsal on Lebanon's border with Syria.

Public insurance programs typically see enrollment increase when the economy slows and people lose their jobs

Medicaid and the State Children's Health Insurance Program provided a safety net for children whose parents' coverage ended or 카지노사이트 - https://staylocal.co/ became too expensive during the economic downturn at the start of the decade, said the Center for Studying Health System Change, a private research organization in Washington, D.C.

"Public insurance clearly picked up the slack," the group said in its report.

A separate Urban Institute report highlighted problems children face when they lack insurance, including missing regular checkups and visiting hospital emergency rooms for routine care. Nearly half of uninsured children had no checkup in the last year, that report said.

The studies were released in tandem by the Robert Wood Johnson Foundation as part of its Covering Kids and Families campaign to boost children's health insurance. The foundation said lack of insurance is especially pronounced among African-American and Hispanic children.

Public insurance programs typically see enrollment increase when the economy slows and people lose their jobs. The study of employer coverage found 67 percent of Americans were insured through their employers in 2001. By 2003, that number had dropped to 63.4 percent.

Sustained economic growth should increase employer - http://www.paramuspost.com/search.php?query=increase%20employer&type=all... coverage, easing the burden on public programs, the health research group said.

As it is, states that have struggled with budget crises because of the economy are trying to cut health program costs, although several million more children are eligible for them. State actions have included restricting eligibility, freezing - http://mondediplo.com/spip.php?page=recherche&recherche=freezing enrollment and increasing participants' contributions, several studies have found.

Federal and state governments share the costs of both Medicaid, which provides health care for the poorest families and children, and SCHIP, for children from working poor families.

The plans cover more than 17 million children, the Johnson foundation said. Eligibility varies by state, but on average, a family of four earning up to $37,000 a year can qualify, it said.By Mark Sherman

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