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The government gave rights to develop it to two companies — Merck and GlaxoSmithKline — and Merck's work is a little farther along, Lowy said

Four years after getting the vaccine, 94 percent of women were protected from infection with the virus that causes most cervical cancers and none had developed worrisome precancerous - https://www.google.com/search?hl=en&gl=us&tbm=nws&q=precancerous&btnI=lucky conditions, a study showed.

"We're thrilled about these results. The immune responses seem to be really long-lasting," said Dr. Eliav Barr, who leads development of the vaccine for Merck and Co. The company plans to seek U.S. Food and Drug Administration approval next year for an expanded version of the vaccine that also could be used to prevent genital warts in both women and men.

The new study was funded by Merck and led by University of Washington researchers who presented results Monday at a meeting of the American Society for Microbiology.

"They showed clear effectiveness," said Dr. Scott Hammer, a Columbia University infectious disease expert who reviewed the work but has no ties to Merck or the study. "This is a very important issue for women's health around the world."

If the vaccine makes it to market, 하남출장안마 - https://www.softanma.com/23-hanam it would be the second developed to prevent cancer. The hepatitis B vaccine has dramatically reduced the number of infections that progress to liver cancer.

Cervical cancer strikes nearly half a million women worldwide each year and kills about half. In the United States, about 15,000 women get it and about 5,000 die.

Virtually all cases are caused by infection with human papilloma virus, or HPV, which is spread through sex. One strain, HPV-16, accounts for about half of all cervical cancers.

A previous study showed that HPV-16 infections were completely prevented in 768 women who had received the Merck vaccine 18 months earlier. None developed precancerous conditions either.

The new study followed 755 of these women for four years after vaccination. HPV-16 infections had taken hold in seven; none developed precancers. In a comparison group of 750 women who received dummy shots, infections took hold in 111 and precancers formed in 12.

Even though protection had waned for a small number of women in the study, the vaccine's effectiveness was still very high, said Dr. Douglas Lowy, a National Cancer Institute scientist who invented the vaccine. The government gave rights to develop it to two companies — Merck and GlaxoSmithKline — and Merck's work is a little farther along, Lowy said

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"Revaccination might be advisable at some point," but it will take more study to know whether that is necessary or would improve effectiveness, he said

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Women in the study were ages 16 to 23 when they received the vaccine, given in three doses over six months

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"Most people think it would be recommended for young adolescents. The idea would be you would immunize people relatively soon before they become sexually active," because the germ is spread through sex, Lowy said

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Meanwhile, Merck is in the final stages of testing an expanded vaccine. Besides HPV-16, it contains strain 18, which causes another 10 percent to 20 percent of cervical cancers, as well as strains that cause genital warts in men and women, and penile and anal cancers in men

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About 25,000 women and men have been enrolled in that study in 34 countries, and results are expected next year, Barr said

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Giving the vaccine to men would not only prevent disease in them but also would prevent infections in their partners, said Steven Projan, a drug development expert with Wyeth who helped review research for the microbiology meeting. The vaccine also might prevent women already infected with HPV from developing cancer, he said.

Those who got real patches also reported more arousal, pleasure and orgasms, and had better self-images

Women on the testosterone patch had sex about four times more than they usually did in two months compared to only one additional session for women given a fake patch containing no hormone, a study found.

Those who got real patches also reported more arousal, pleasure and orgasms, and had better self-images.

"We found an increase in activity, an increase in desire and a decrease in distress," said Dr. Robin Kroll, 카지노사이트 - http://www.espritwhisperingridge.com/ a Seattle gynecologist who reported results of the study Tuesday at a meeting of infertility specialists. The research was sponsored by Procter & Gamble Pharmaceuticals, which is developing the patch, called Intrinsa, with Watson Pharmaceuticals Inc.

It was the first big test of the patch in women who went through menopause naturally and complained of low sex drive. A previous study in women who became menopausal because of surgery found similar results, and the companies already have asked the federal Food and Drug Administration to approve its use for those women.

"The testosterone patch looks very promising. It may be the answer for what women are looking for for a libido lag in menopause," said Dr. Marian Damewood, a University of Pennsylvania gynecologist who is president of the American Society for Reproductive Medicine.

As many as 30 million American women will have gone through natural menopause by 2005 and another 10 million will be menopausal because of having their ovaries removed, Procter & Gamble estimates.

Lack of interest in or pleasure from sex is a big problem for such women, partly because of the decline in testosterone. Even though men make far more of this hormone than women, females still need a certain amount of it to have healthy sex lives, experts say.

Taking testosterone pills isn't advised because it can cause excessive hair growth, liver complications and other problems. Testosterone creams that are applied to the inner thigh are an option, but they've gotten little scientific study, Damewood said.

She had no role in the patch study, which involved 549 women in Seattle, Denver, Boston, Canada and Australia, averaging 54 years old, who were upset because they didn't feel like having sex. They were assigned to get either hormone or placebo patches. All kept logs of their sexual activities and filled out standard questionnaires about their feelings.

Those on the hormone patch - http://photobucket.com/images/hormone%20patch improved in all measures. Side effects were mild and reported by three out of four women in each group - mostly excess facial hair and red or irritated skin from the patch, Kroll said.

"None of those patients wanted to stop taking the testosterone," she added.

The experiment - https://www.behance.net/search?content=projects&sort=appreciations&time=... was done over six months, the longest period of time the patch has been tested.

Meanwhile, a survey of 2,000 American women sponsored by Procter & Gamble and done by the Robert Wood Johnson Medical School in New Jersey found that one in three naturally menopausal women reported lackluster sex lives, but only one in 10 said it upset them.

By Marilynn Marchione

John H

"There arrives a point in time when the procedure should simply be done. We submit that that time is now," the researchers wrote in an article scheduled for publication Friday in The American Journal of Bioethics. The procedure attaches the face of a dead donor to someone with a severely disfigured face, such as a burn or accident victim.

The doctors said they don't have a prime candidate for the procedure, and they are not actively screening for candidates.

They have submitted an application to an institutional review board in the Netherlands and are nearly ready to submit one to an independent board in the United States.

The Louisville doctors said they would not perform the transplant without approval from one of the boards, 전주출장안마 - https://www.opmassage.com/16-jeonjuu which are designed to protect medical research subjects' rights.

"The people we're considering are people who have no other options," Dr. John H. Barker, director of plastic surgery research at the University of Louisville, told The Courier-Journal newspaper.

Nichola Rumsey of the University - http://www.google.com/search?q=University&btnI=lucky of the West of England, an expert in psychosocial issues in medicine, said the ethical issues of the procedure have yet to be fully explored. She wrote one of 14 essays written in reaction to the article and published in the bioethics journal.

"Previous research and current understanding indicate that the psychological risks are more complex and extensive than the Louisville team suggest," she wrote. "I have no wish to minimize the distress experienced by many people with severe disfigurements, but to my mind, the current risk/benefit ratio ... is dubious at best."

Besides Louisville, such transplants are being considered by teams in Cleveland, England and France.

"I want to assure them that our government is doing everything possible to help older Americans and children get their shots despite the major manufacturing defect that caused this problem," he said

The flu season typically peaks in January or later. It takes two weeks for people to develop immunity after being vaccinated, which should be done in October or November, according to the Centers for Disease Control and Prevention.

So while the U.S. government is searching all over the world for more vaccine, it is unclear how helpful the extra doses will be if they don't arrive until next year.

The extra doses were ordered after British regulators closed a plant making half of the flu vaccine the United States requested for 아산출장마사지 - https://www.anmapop.com/%ec%95%84%ec%82%b0%ec%b6%9c%ec%9e%a5%ec%83%b5%cf... this season.

The vaccine shortage has had wide-ranging effects, from Canada to Capitol Hill to the campaign trail.

Clinics and pharmacies across the border are offering to inoculate U.S. residents, Margaret Holmen and others from the Powers Lake Senior Citizens Center in Bismarck, N.D., have been talking about going to Canada for their shots.

"Everybody here is thinking about it," said Holmen, the senior center's manager. "We hear on the news that we should be patient, but we don't know what to do."

Word of Canada's vaccine availability is spreading quickly. Eighty Americans showed up for flu shots Tuesday at Henders Drug in Estevan — located about 9 miles north of the North Dakota border — although the store's newspaper advertisement hadn't even run yet.

"I suspect there will be a lot more," said Larry Preddy, pharmacist and co-owner of the store. He charges Americans the same price as Canadians — $15 Canadian or about $12.

Urgent Care Niagara's Fort Erie clinic, just across the border from Buffalo, said it would vaccinate 100 Americans a day, for around $40 each, squeezing them in among Canadian patients who got first priority.

Meanwhile, The Washington Post reports that despite the government's request that young, healthy people forego the shot this year, flu vaccine is readily available on Capitol Hill and the physician there is advising all lawmakers to get it. Already, 2,000 shots have been dispensed there, down from 9,000 a year ago.

In the Sunshine state, a vaccination campaign by Get Healthy Florida was put on hold on the order of the Food and Drug Administration after it was discovered that the vaccine was coming from a foreign producer, not the domestic one that was expected.

On the campaign trail, Sen. John Kerry, President Bush's Democratic challenger, has said the administration failed to heed warnings about a potential shortage.

"If you can't get flu vaccines to Americans, how are you going to protect them against bioterrorism? If you can't get flu vaccines to Americans, what kind of health care program are you running?" Kerry said.

In Florida, Mr. Bush sought to ease Americans' concerns. "I want to assure them that our government is doing everything possible to help older Americans and children get their shots despite the major manufacturing defect that caused this problem," he said.

Chiron Corp. was expected to provide the United States with 46 million to 48 million doses of flu vaccine, nearly half the supply the government anticipated needing. But British regulators closed Chiron's Liverpool facility because of contamination.

That left the United States with about 55 million doses from its second manufacturer, Aventis Pasteur. At a news conference Tuesday, Aventis Pasteur announced it could produce another 2.6 million doses. The extra vaccine won't be ready for distribution until January.

"We're waging a comprehensive and aggressive response," Health and Human Services Secretary Tommy Thompson told a news conference. "We have good reason to be optimistic in our ability to deal with the flu season and protect the most vulnerable from its harsh effects."

He said there was enough antiviral medicine available to treat 40 million people, shortening illness in people sick with the flu and preventing illness in healthy people.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Disease, said Wednesday he believes the additional shots will arrive in time to help.

The flu season likely will "peak at the end of the December, the beginning of January, but it goes well through February and sometimes into March," he said on the CBS News Early Show.

"So, any amount of doses that one can get, even as late as January, clearly will be very helpful, particularly if we have a very active flu year," Fauci said.

Between vaccines and antiviral drugs, enough medicine will be available to treat 100 million people this flu season, Thompson said. Federal authorities have asked that healthy adults refrain from getting vaccinated to leave enough for those at greatest risk: the very young, the very old and people with chronic illnesses.

Meanwhile, officials are looking "throughout the world" for additional vaccine, said Lester Crawford, Food and Drug Administration acting commissioner.

Crawford said the FDA would give expedited review to flu vaccine produced by ID Biomedical of Canada. The expedited review — "weeks, rather than months" — means the 1.5 million Canadian flu shots - http://www.adobe.com/cfusion/search/index.cfm?term=&flu%20shots&loc=en_u... could reach Americans this season, he said.

They have submitted an application to an institutional review board in the Netherlands and are nearly ready to submit one to an independent board in the United States

"There arrives a point in time when the procedure should simply be done. We submit that that time is now," the researchers wrote - http://www.fool.com/search/solr.aspx?q=researchers%20wrote in an article scheduled for publication Friday in The American Journal of Bioethics. The procedure attaches the face of a dead donor to someone with a severely disfigured face, such as a burn or accident victim.

The doctors said they don't have a prime candidate for the procedure, and they are not actively screening for candidates.

They have submitted an application to an institutional review board in the Netherlands - http://www.healthncure.net/?s=Netherlands and are nearly ready to submit one to an independent board in the United States.

The Louisville doctors said they would not perform the transplant without approval from one of the boards, which are designed to protect medical research subjects' rights.

"The people we're considering are people who have no other options," Dr. John H. Barker, director 구미출장마사지 - https://www.anmastar.com/%ea%b5%ac%eb%af%b8%ec%b6%9c%ec%9e%a5%ec%83%b5%c... of plastic surgery research at the University of Louisville, told The Courier-Journal newspaper.

Nichola Rumsey of the University of the West of England, an expert in psychosocial issues in medicine, said the ethical issues of the procedure have yet to be fully explored. She wrote one of 14 essays written in reaction to the article and published in the bioethics journal.

"Previous research and current understanding indicate that the psychological risks are more complex and extensive than the Louisville team suggest," she wrote. "I have no wish to minimize the distress experienced by many people with severe disfigurements, but to my mind, the current risk/benefit ratio ... is dubious at best."

Besides Louisville, such transplants are being considered by teams in Cleveland, England and France.

"They're being given as toys without recognition that there may be a serious injury risk," said report author Dr

Nonpowder guns kill an average of four Americans yearly, and from 1990 to 2000, there were 39 such deaths — 32 of children younger than 15, according to a report in November's issue of Pediatrics.

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The report, published Monday, comes just two weeks after the BB gun death of an 8-year-old South Carolina boy accidentally killed by a 13-year-old friend. The pellet pierced the boy's heart, said Richland County Coroner Gary Watts.

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"These are not the kinds of BB guns that I grew up with," Watts said. Today's BB guns "are extremely high-powered," and some can shoot with a velocity nearly matching a .22 caliber rifle, Watts said.

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Nonpowder guns - http://www.squidoo.com/search/results?q=Nonpowder%20guns include powerful air rifles introduced in the 1970s and 서산출장마사지 - https://www.anmapop.com/%ec%84%9c%ec%82%b0%ec%b6%9c%ec%9e%a5%ec%83%b5%cf... paintball pistols used in war games. They're sometimes described as fake guns and often given to children as gifts, but the report says they can cause internal injuries.

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Nationally, an estimated 21,840 injuries related to nonpowder guns were treated in emergency departments in 2000 — most in children aged 5 to 14, according to the report prepared by the American Academy of Pediatrics' Committee on Injury, Violence and Prevention

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Data from the Centers for Disease Control and Prevention show there were 19,163 nonpowder gun injuries last year

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Most states have laws or regulations governing nonpowder guns. New York's is one of the strictest, prohibiting the purchase or unsupervised use by someone younger than 16 years, the Pediatrics report said

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While some models of air guns and BB guns are marketed specifically to youngsters, manufacturers and sellers also stress that they should be handled like legitimate firearms

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The gun involved in the South Carolina shooting was a present from the older boy's parents, who had hoped it would lift his spirits after his own brother's recent death in a car accident, Watts said

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"They're being given as toys without recognition that there may be a serious injury risk," said report author Dr. Danielle Laraque, a New York pediatrician.

Data from the Centers for Disease Control and Prevention show there were 19,163 nonpowder gun injuries last year

Nonpowder guns kill an average of four Americans yearly, and from 1990 to 2000, there were 39 such deaths — 32 of children younger than 15, according to a report in November's issue of Pediatrics.

>\

>
The report, published Monday, comes just two weeks after the BB gun death of an 8-year-old South Carolina boy accidentally killed by a 13-year-old friend. The pellet pierced the boy's heart, said Richland County Coroner Gary Watts.

>\

>
"These are not the kinds of BB guns that I grew up with," Watts said. Today's BB guns "are extremely high-powered," and some can shoot with a velocity nearly matching a .22 caliber rifle, Watts said.

>\

>
Nonpowder guns include powerful air rifles introduced in the 1970s and paintball pistols used in war games. They're sometimes described as fake guns and often given to children as gifts, but the report says they can cause internal injuries.

>\

>
Nationally, an estimated 21,840 injuries related to nonpowder guns were treated in emergency departments in 2000 — most in children aged 5 to 14, according to the report prepared by the American Academy of Pediatrics' Committee on Injury, Violence and Prevention

r>

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Data from the Centers for Disease Control and Prevention show there were 19,163 nonpowder gun injuries last year

r>

r>
Most states have laws or regulations governing nonpowder guns. New York's is one of the strictest, prohibiting the purchase or unsupervised use by someone younger than 16 years, the Pediatrics report said

r>

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While some models of air guns and BB guns are marketed specifically to youngsters, manufacturers and sellers - http://imgur.com/hot?q=sellers also stress that they should be handled like legitimate firearms

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The gun involved in the South Carolina shooting was a present from the older boy's parents, 군산출장안마 - https://www.opmassage.com/17-gunsann who had hoped it would lift his spirits after his own brother's recent death in a car accident, Watts said

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"They're being given as toys without recognition that there may be a serious injury risk," said report author Dr. Danielle Laraque, a New York pediatrician.

FDA officials did not immediately return phone calls seeking comment

Vioxx, heavily marketed as an arthritis drug, was pulled from the market last week after its maker announced that a study showed it doubled the risk of heart problems. But the U.S. Food and Drug Administration said similar prescription drugs were safe.

On Wednesday, the European Medicines Agency in London announced it would review drugs similar to Vioxx. And researchers writing in the New England Journal of Medicine voiced their concerns as well with such drugs as Pfizer's popular Celebrex.

As CBS News Correspondent Elizabeth Kaledin reports, the study in Thursday's New England Journal of Medicine is now questioning the safety of other drugs in the same class...drugs known as COX 2 inhibitors..Dr. Garret FitzGerald has been studying - http://browse.deviantart.com/?q=studying the drugs for 5 years.

"There have been suggestions in the past that indeed there are possibilities of cardiovascular problems with other members of this class,'' he told Kaledin.

The medical journal published two reports on the issue Wednesday on the Internet, ahead of their planned publication, because of their public health importance.

Studies done five years ago when Celebrex and Merck & Co.'s Vioxx were approved suggest that the same mechanism that inhibits inflammation and makes the drugs easier on the stomach than traditional painkillers also blocks a substance that prevents heart problems, FitzGerald, a University of Pennsylvania cardiologist who led the studies, which were designed by him but funded by the drug companies.

"I believe this is a class effect," meaning that the problem also applies to Celebrex and Pfizer's newer, similar drug, Bextra, which remain on the market.

He called on the FDA to change its advice to patients and doctors to reflect the new safety concerns. In a separate report also released by the medical journal, Dr. Eric Topol of the Cleveland Clinic chastises the FDA for not requiring Merck to do studies investigating heart problems with Vioxx when hints of them first appeared years ago.

Pfizer's medical director, Dr. Gail Cawkwell, insisted that its drugs are safe.

"The data for Celebrex is robust and 삼척출장마사지 - https://www.anmastar.com/%ec%82%bc%ec%b2%99%ec%b6%9c%ec%9e%a5%ec%83%b5%c... exceeds, in the length of patients in studies and in the size of studies, the data Vioxx has," she said.

She called FitzGerald's contention "an interesting theory," but said, "there is no evidence" of increased risk of heart problems among the 75 million Americans who have taken Celebrex. Long-term studies are not yet available on Bextra, which was approved in 2001.

FDA officials did not immediately return phone calls seeking comment.

When Merck voluntarily withdrew Vioxx, FDA officials said heart problems were unique to that drug and that the mechanism underlying them wasn't known.

But FitzGerald and colleagues published two studies in 1999 and another in 2001 suggesting that by selectively blocking one of the two substances called prostaglandins that lead to inflammation, these so-called cox-2 inhibitors were sparing the stomach at the expense of the heart.

"There's a good prostaglandin and a bad prostaglandin as far as the heart is concerned," he explained.

Suppressing both, as older painkillers like aspirin and other non-steroidal anti-inflammatory drugs, or NSAIDS do, helps the heart. But shutting down just the "good" one raises the risk of high blood pressure, hardening of the arteries and clotting, he reports.

The studies will be published in the Oct. 21 print edition of the medical journal.

"A lot of (schools) are saying we'd love to do it, but give us the resources," Combs said

The call for bolder action in schools follows the Institute of Medicine's recommendations last month calling for a wide-ranging attack on childhood obesity by involving parents, schools, communities and the government.

Estimates are that more than 15 percent of American children are very overweight, or obese.

Laura Hayman, a nurse and professor who wrote the heart association statement, said national data show about 80 percent of children aren't getting the recommended five or more servings of fruits and vegetables each day. She also said that 44 percent of high school students aren't in physical education - http://www.homeclick.com/web/search/search.aspx?Ntt=physical%20education classes.

"Through schools, hopefully you can reach the children, teachers and parents," said Hayman, 고양출장마사지 - https://www.startopanma.com/%ea%b3%a0%ec%96%91%ec%98%a4%ed%94%bc%ea%b1%b... who teaches at New York University and Lenox Hill Heart and Vascular Institute of New York.

Experts agree that the schools - http://www.express.co.uk/search/schools/ are a good place to start.

Judith Young, of the Virginia-based nonprofit American Alliance for Health, Physical Education, Recreation and Dance, said educating kids on the issue is critical. "If we don't teach them how to keep themselves healthy, then all the other things kind of don't matter."

The heart association statement, published in the journal Circulation, calls for more phys ed classes, heart-healthy meals and a tobacco-free environment from preschools through 12th grade and during after-school programs.

Dr. Catherine L. Webb, a professor of pediatrics at Northwestern University's Feinberg School of Medicine in Chicago, points out that families are often collectively obese.

"When a child starts to bring home knowledge, then the family I think will jump on the bandwagon," said Webb, who works on a heart association council focusing on cardiovascular disease among young people

Obesity is linked to diabetes, high blood pressure, high cholesterol and other problems, and it's a risk factor for cardiovascular disease, Hayman said.

The heart association recommendations call for teaching kids the major risk factors for cardiovascular disease and ways to avoid it.

The group also recommends that physical education be required at least three times a week from kindergarten through 12th grade — with 150 minutes in school each week for elementary students and at least 225 minutes per week for middle school students.

According to the recommendations, school meals should meet heart-healthy guidelines.

Texas Agriculture Commissioner Susan Combs, who issued a school nutrition policy that took effect this year restricting fried and fatty servings and setting other food rules, said that school administrators understand the importance of physical education and nutrition, but they are dealing with limited resources.

More health education, for instance, might cost money for printed materials.

"A lot of (schools) are saying we'd love to do it, but give us the resources," Combs said.

They're sometimes described as fake guns and often given to children as gifts, but the report says they can cause internal injuries

Nonpowder guns kill an average of four Americans yearly, 군포출장마사지 - https://www.anmapop.com/%ea%b5%b0%ed%8f%ac%ec%b6%9c%ec%9e%a5%ec%83%b5%cf... and from 1990 to 2000, there were 39 such deaths — 32 of children younger than 15, according to a report in November's issue of Pediatrics.

>\

>
The report, published Monday, comes just two weeks after the BB gun death of an 8-year-old South Carolina boy accidentally killed by a 13-year-old friend. The pellet pierced the boy's heart, said Richland County Coroner Gary Watts.

>\

>
"These are not the kinds of BB guns that I grew up with," Watts said. Today's BB guns "are extremely high-powered," and some can shoot with a velocity nearly matching a .22 caliber rifle, Watts said.

>\

>
Nonpowder guns include powerful air rifles introduced in the 1970s and paintball pistols used in war games. They're sometimes described as fake guns and often given to children as gifts, but the report says they can cause internal injuries.

>\

>
Nationally, an estimated 21,840 injuries related to nonpowder guns were treated in emergency departments in 2000 — most in children aged 5 to 14, according to the report prepared by the American Academy of Pediatrics' Committee on Injury, Violence and Prevention

r>

r>
Data from the Centers for Disease Control and Prevention show there were 19,163 nonpowder gun injuries last year

r>

r>
Most states have laws or regulations governing nonpowder guns. New York's is one of the strictest, prohibiting the purchase or unsupervised use by someone younger than 16 years, the Pediatrics report said

r>

r>
While some models of air guns - http://www.buzzfeed.com/search?q=air%20guns and BB guns are marketed specifically to youngsters, manufacturers and sellers also stress that they should be handled like legitimate firearms

r>

r>
The gun involved in the South Carolina shooting was a present from the older boy's parents, who had hoped it would lift his spirits after his own brother's - http://www.covnews.com/archives/search/?searchthis=brother%27s recent death in a car accident, Watts said

r>

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"They're being given as toys without recognition that there may be a serious injury risk," said report author Dr. Danielle Laraque, a New York pediatrician.

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